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Find patient medical information for Modafinil (Provigil) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Provigil (modafinil) is used for excessive sleepiness caused by narcolepsy, sleep apnea, and shift work. Learn about side effects, warnings, dosage, and more. Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant medication used to treat narcolepsy, sleep apnea, and shift work sleep disorder. [3][7][15] It is taken by mouth. [3][7] Modafinil is a first-line treatment for narcolepsy in the United States and Europe. [16][17] The mechanism of action is not fully understood, but modafinil acts mainly as … Modafinil is used to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness) or shift work sleep disorder (sleepiness during scheduled waking hours and difficulty falling asleep or staying asleep during scheduled sleeping hours in people who work at night or on rotating shifts). Modafinil is also used along with breathing devices or other … Modafinil (Provigil) is a medication that treats excessive tiredness caused by narcolepsy, sleep apnea and shift work sleep disorder. Modafinil (Provigil) is a controlled substance, which means that it's more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time. The medication remains unchanged, and patients will continue to receive the same formulation they have been prescribed. 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